For years, the media has speculated on Jennifer Aniston’s ‘choice’ not to have children and now she has finally shared the truth about her struggles with IVF and trying to conceive.

In an interview published in Allure this month, she spoke candidly about her attempts to get pregnant with IVF during her late 30s and 40s.

“I was trying to get pregnant. It was a challenging road for me, the baby-making road,” she said.

“All the years and years and years of speculation… It was really hard. I was going through IVF, drinking Chinese teas, you name it. I was throwing everything at it.”

Jennifer also revealed that she wished that someone had advised her to freeze her eggs at an earlier age: “I would’ve given anything if someone had said to me: ‘Freeze your eggs. Do yourself a favour.’ You just don’t think it. So here I am today. The ship has sailed.”

So, why is your age such an important when it comes to egg freezing?

A study carried out by Imperial College London researchers published earlier this year found that women who freeze their eggs at 40 are unlikely to have a successful live birth. This supports the advice from Human Fertilisation & Embryology Authority (HFEA) that age is the key factor in egg freezing success.

The Imperial College London study suggested that women should be encouraged to undergo elective oocyte cryopreservation, commonly known as egg freezing, before the age of 36 to mitigate age-related fertility decline.

Egg freezing is becoming more and more popular as a fertility preservation and the results from the UK study suggest women should be encouraged to undergo egg freezing much earlier than the evidence suggests they are currently doing.

Egg freezing FAQs:

  1. What is the best age to freeze your eggs?

Fertility begins to decline from the age of 35, this decline becomes more rapid once you reach your mid-30s and so your optimum age to freeze your eggs would be your late 20s and early 30s.

  1. What happens during the egg freezing process?

Our fertility nurses are on hand to take you through the whole process. This usually starts with hormonal injections on day two of your cycle for approximately two weeks. We will carry out regular scans to monitor your progress and, when the follicles have reached the right stage of development, we give you a trigger injection to encourage final maturation of the eggs within the follicles.

Egg collection is then scheduled 36-38 hours later. This is a minor surgical procedure lasting between 20 and 30 minutes, carried out under intravenous sedation. The eggs are checked and then frozen and stored for your use in the future.

  1. How long can my eggs be stored?

Previously, eggs, sperm or embryos could only be stored for up to ten years except in cases of premature infertility or if undergoing medical treatment which could affect fertility. On 1 July 2022, these rules changed and now the law permits you to store eggs, sperm or embryos for up to 55 years, although you need to renew your consent every ten years.

If you have more questions about egg freezing and our success rates, call +44 (0) 203 263 6025 or email admin@ariafertility.co.uk to arrange a consultation with one of our fertility specialists.

This week is Fertility Awareness Week in the UK. With 3.5 million people here facing fertility challenges, Fertility Network UK’s aim is to improve awareness and provide support at whatever stage of the journey you’re at.

Among other initiatives they are running a series of webinars during the week, touching on important fertility issues, finishing on Friday with a lunchtime webinar with Aria’s own Stuart Lavery. Friday’s theme will be #TalkFertility and will signpost the help available those experiencing fertility struggles so you don’t have to suffer in silence or feel unsupported.

Register for Friday’s webinar with Mr Stuart Lavery >

Yesterday’s theme was #FertilityFairness and tied into a new survey commissioned by Fertility Network UK into the postcode lottery that is fertility treatment in the UK. Only Scotland offers the recommended three full IVF cycles and almost two-thirds of respondents to the survey said they had to pay for their own treatment.

The emotional impact of IVF treatment and was also surveyed and worryingly four in 10 respondents said they experienced suicidal feelings. The vast majority at 83% said they felt sad, frustrated and worried often

Gwenda Burns, chief executive of Fertility Network UK, said: “Fertility patients encounter a perfect storm: not being able to have the child you long for is emotionally devastating.

“But then many fertility patients face a series of other hurdles, including potentially paying financially crippling amounts of money for their necessary medical treatment, having their career damaged, not getting information from their GP, experiencing their relationships deteriorate, and being unable to access the mental support they need.

“This is unacceptable. Infertility is a disease and is as deserving of medical help and support as any other clinical condition.”

The rest of the upcoming webinars this week are as follows:

Tuesday 1 November
#FertilityintheWorkplace

Most employers in the UK do not recognise fertility treatment as a necessary medical treatment and there is no legal right to time off work for fertility appointments. Fertility Network UK is calling for employers to recognise fertility treatment as a clinical necessity and to provide appropriate medical leave.

Register for Tuesday’s Webinar >

Wednesday 2 November
#HimFertility

Male factor fertility is a common reason for infertility yet often men’s fertility is not tested in the initial stages resulting in unnecessary delays. Fertility Network UK is calling for men’s fertility to be tested in a timely manner at the same time as a woman’s fertility is explored.

Register for Wednesday’s webinar >

Thursday 3 November
#FertilityEd

Fertility education in schools should be expanded in scope so teenagers and young adults understand fertility isn’t guaranteed and that treatments such as IVF and egg freezing do have some limits.

Register for Thursday’s webinar >

For more advice and support on any of the issues we’ve touched on here, call +44 (0) 203 263 6025 to discuss further.

Traditional Chinese Medicine is an ancient medical system that treats imbalances in the body at physical, mental and energetic level. It focused on the root cause of the disease. The treatments have a cumulative effect, which means that each treatment builds on the last one. That is why we always recommend having a series of 6 or 12 consecutive treatments to fully enjoy the long-lasting health benefits of Traditional Chinese Medicine.

Eca Brady, an expert physician of Traditional Chinese medicine, has run a successful practice on Harley Street for over 11 years, focusing on IVF support, infertility, pregnancy, birth and post-natal recovery.

In her treatments she will use acupuncture, Chinese herbal medicine, dietary and lifestyle advice.

“Herbal medicine has become very popular currently, and it can be a powerful force for healing when done appropriately.  Each patient, after a detailed consultation and a diagnostic, when necessary, will be prescribed a personalised formula which will target her or his own imbalances.

A lot of knowledge and experience goes into writing an herbal formula. Each plant is chosen carefully for their own benefit but also for how well they would work in the prescribed combination with the other herbs.  A wrong herb can potentially cause side effects and a lot of damage if it is used over a long period of time,” Eca explains.

“It is popular now to take herbs as supplements like ashwagandha or turmeric which are often presented as beneficial for all sorts of conditions, but sometimes taking these herbs in high doses without a proper diagnostic can do more damage than good. I have seen in clinic many new patients presenting with side effects from taking these herbs in very high quantities over long periods of time.”

Can Chinese herbal medicine boost your IVF treatment?

Chinese herbal medicine has been used for centuries to enhance fertility by regulating the endocrine system, balancing hormones, nourishing the blood and reducing stress.

Eca believes that each patient should prepare before their IVF procedure for at least one month and ideally three months, using Traditional Chinese Medicine; not only to increase the chances of a successful IVF and to achieve an easy pregnancy, but also for the health benefits for your baby.

“I always follow the lead of your fertility doctor. It is not necessarily for me to have direct contact with them, but I always request that my patients ask permission from their doctor to have the treatments.

“The herbal medication is more often used in preparation to IVF, not necessarily during.  Herbal medicine is safe but always under the supervision of a qualify herbalist.”

As Eca points out, the quantity of herbs in supplements purchased at natural food shops can often exceed what she would normally prescribe to her patients: “The amount of turmeric in one pill that you buy from Holland & Barrett can be too much. When I make up a formula, I might use 8 grams of turmeric for a monthly prescription in combination with other herbs.  If you go to H&B and take three pills in a day, you’ve taken the same amount that I would be prescribing over a month.”

To find out more about Eca and arrange a consultation, please click here. For more information on the individual practitioners and organisations offering support, advice, and information to those undergoing fertility treatment, please visit our Support Hub.

Embarking on fertility treatment can be overwhelming and stressful, so it helps to be prepared in terms of what to expect during your first fertility consultation and to know what questions you should ask.

Many patients we see at Aria Fertility have undergone treatment on the NHS or at other fertility clinics and so may have already undergone various tests and received a diagnosis. Some are at the start of their fertility journey or wish to learn more about fertility preservation options such as egg freezing. Whatever stage you are at, one of the most important considerations at your first consultation is whether you feel comfortable with your fertility specialist.

Your initial consultation will usually last 30 minutes, and you will be asked about your fertility journey up to this point, as well as in-depth questions on your medical and family history, either as an individual or for both you and your partner if you are attending as a couple.

This first visit will be the opportunity to get to know your fertility doctor and the clinic and for them to get to know you and it is essential you feel comfortable enough to ask questions.

3 questions to ask in your first fertility consultation

  1. What diagnosis might explain why we haven’t been able to conceive?

Your doctor may not be able to tell you the exact cause of infertility at the first visit as we may need to arrange additional testing to help us determine the cause.

However, be aware that potentially one in five cases of fertility cannot be explained. Unexplained infertility is thought to affect 15% to 30% of couples and individuals and is when they have undergone all the appropriate tests and no cause is found. It is most likely to involve issues with egg or sperm quality or problems with the uterus or fallopian tubes that aren’t identifiable during normal fertility testing. Unexplained fertility can still be successfully treated with fertility drugs, IUI and IVF.

  1. What treatments do you recommend for us and what are their potential success rates?

At Aria Fertility we offer several different treatment options. This could be fertility drugs as a standalone treatment or in combination with IUI or IVF. Your fertility doctor will be able to give you information on the success rates of the clinic and advice on how successful a particular treatment option is likely to be, taking into account your age and medical history.

  1. How much does IVF treatment cost?

It can often be embarrassing to ask questions about cost, but fertility treatment is a significant investment. Once a treatment pathway is recommended by our doctors, our Patient Coordinator Team will provide you with a comprehensive breakdown of costs, including any add-ons or medication that have been discussed.

At Aria Fertility, we believe in 360 support. Once you’ve made the informed choice to proceed, our dedicated team, which is composed of your fertility specialist, fertility nurse and patient coordinator, will help you chart the course of your fertility treatment. You will also have the support of a fertility coach who can advise you on nutrition, lifestyle changes, and complementary medicine as a supplement to your medical care.

To arrange a consultation with Aria Fertility, call +44 (0) 203 263 6025.

According to HFEA, the Human Fertilisation and Embryology Authority, cycles of egg freezing have increased tenfold in the UK in the space of a decade, as more and more women start families later in life and look for ways to preserve their fertility.

Now, a large-scale US report on elective fertility preservation outcomes has found that using frozen eggs are a more efficient option than IVF with fresh eggs or embryos at a later age.

The researchers found that 70% of women who froze eggs when they were younger than 38 and then thawed at least 20 eggs later went on to have a baby. In comparison, fewer than 30% of women undergoing IVF at age 40 using fresh eggs became pregnant and fewer than 20% gave birth to live babies.

“Our findings shed light on the factors that track with successful births from egg freezing, which include careful screening of embryos to be thawed and implanted,” says lead author Sarah Druckenmiller Cascante at the department of obstetrics and gynaecology at NYU Langone.

“A better understanding of the live birth rate from egg freezing for age-related fertility decline is necessary to inform patient decision-making.”

Within the study, published in the journal Fertility and Sterility, 543 patients participated with an average age of 38 years old at the time of the first egg freeze, which is older than the generally recommended age to freeze eggs which is 35 years old or younger.

Overall, the study established that 39% of women between 27 and 44 years old, with a majority between 35 and 40 years old at egg freeze, had a least one child from their frozen eggs. Across all ages, women who thawed more than 20 mature eggs had a 58% live birth rate and women under 38 years old who had 20 or more mature eggs thawed achieved a 70% live birth rate per patient.

The study also showed that preimplantation genetic screening with embryos from frozen and eventually thawed eggs resulted in lower miscarriage rates and higher live birth rates per transfer.

The growing popularity of egg freezing

Awareness of fertility preservation is gaining traction in the media with celebrities such as Love Island’s Amy Hart speaking candidly about their decision to freeze eggs. There are many reasons why a woman may choose to delay starting their family, which may include not being in the right place in terms of their relationship or career, or not in a financial position to proceed at this point.

The improvement in the clinical methods used to collect the eggs, assess them for maturity and viability, and then freeze them has also contributed to the success of egg freezing. Previously, the slow freezing process had a survival rate of approximately 30%, but the current method of vitrification means survival rates of over 90% typically.

For more advice on the benefits of egg freezing, call +44 (0) 203 263 6025 to arrange a consultation.

Since the birth of the first baby conceived using in vitro fertilisation in the UK more than four decades ago there have been significant advances, but for many couples IVF remains an emotionally and physically challenging process that may not lead to conception.

Recently, much of the focus has been on the role that Artificial Intelligence (AI) can play in improving the current live birth rate per embryo transferred. This currently stands at 25% and 19% respectively for patients aged 35 to 37 and 38 to 39 according to the most recent figures from HFEA.

“Artificial Intelligence (AI) for gamete and embryo selection has marked the start of a new era in IVF and is here to stay,” explains Xavier Viñals Gonzalez, Aria’s Senior Clinical Embryologist and Laboratory Manager.

“We can now get a deeper level of information which was not available to embryologists before. AI systems are already key for research and development in the field of IVF and will certainly improve our understanding of egg and sperm quality and embryo development.”

AI and IVF

Artificial intelligence describes technology that mimics human cognitive capacity to make predictions based on evolving data. In the IVF lab, it can aid the embryologist to make a rapid and accurate assessment of the health of a gamete or embryo.

Artificial intelligence is used as extension to time lapse monitoring that takes images of embryos at intervals of ten minutes, allowing our embryologists to monitor every stage of embryo development.

AI systems can review a massive amount of data, far more than humans can process, including hundreds of images from each developing embryo. Some AI algorithms are trained to predict clinical pregnancy, others to unveil genetic make-up of the embryos.

By analysing thousands and thousands of these time lapse images and comparing those that go onto successful outcome to those that don’t, AI uses this data to grade the embryos with greatly improved accuracy.

This process is always overseen by our embryologists who review the selection process before implantation but, as Xavier explains, “the assistance of AI systems to daily laboratory workflow will offer patients outcome optimisation and provide better understanding of their chances along reproductive journey.”

A study published last year in the Journal of Assisted Reproduction and Genetics discussed how AI can be used as an essential component in a fertility clinic lab’s quality management system. It could provide “systemic, early detection of adverse outcomes, and identify clinically relevant shifts in pregnancy rates”.

Currently, Aria Laboratories continue to evaluate the efficacy of time-lapse parameters and artificial intelligence algorithms as predictors of embryo potential with the main focus on delivering high success rates to our patients, whilst minimising multiple pregnancy. To learn more about the use of AI in the Aria Fertility lab, call (0) 203 263 6025 to arrange a consultation.

Every June the focus is on male health as Men’s Health Awareness Week campaigns to heighten awareness of preventable health problems and encourage men to choose healthier lifestyle choices.

It’s estimated that male infertility is a factor in 40 to 50% of infertility cases and, in recent years, there has been much research into the crucial role that modifiable lifestyle factors play.

One key lifestyle factor that is known to affect male fertility is being overweight, but the good news is that the damage is reversible. A new study has found that obese men who lose weight – and are able to keep it off – can increase their sperm count by 40%.

Danish researchers studied a group of 47 obese men and their findings were recently published in the journal Human Reproduction. The men were placed on a low-calorie diet for eight weeks and lost on average of 36 lbs. Sperm counts were measured both before and after the diet and discovered a substantial increase in sperm count.

“This study shows that sperm concentration and sperm count were improved after a diet-induced weight loss in men with obesity,” concluded researcher Signe Sørensen Torekov, a professor of biomedical sciences at the University of Copenhagen in Denmark.

The study also revealed the importance of committing to these lifestyle changes – the men were revisited a year later, and half the men had regained the weight, resulting in a corresponding decline in their sperm count.

Other lifestyle factors that could cause male infertility

Obesity can affect hormone levels causing reduced sperm production and concentration and there may also be a link between a raised BMI and both sperm motility and morphology (movement and shape) and DNA damage. However, being overweight isn’t the only lifestyle factor that is known to affect male fertility. Smoking, stress, excessive alcohol consumption, and recreational drugs can all play a role.

Male fertility assessments

The focus of this year’s Male Health Awareness week is the importance of a Man MOT, with guidance on how to check your mental and physical wellbeing and why you should undergo regular health screening checks.

At Aria Fertility, we offer a range of male fertility investigations. The first step is a review of your general health and your medical history. You will then be asked to provide a semen sample and we assess the quality of your sperm, including viscosity, volume, concentration, motility, and morphology. This information is used to advise you of the appropriate fertility treatment plan.

Other tests include those to identify microbes in semen plasma, DNA damage, or sperm maturity.

To book your male fertility assessments, call +44 (0) 203 263 6025.

In vitro fertilisation and other fertility treatments are an often-gruelling process, with a huge impact both physically and emotionally on both men and women. This experience is further compounded for women by discrimination in the workplace, according to a MP who is campaigning for new employee protection for women undergoing IVF.

The Conservative MP for Cities of London and Westminster Nickie Aiken wants to make it illegal for employers to side line or sack women who are trying to conceive through IVF and are having to take time off for fertility-related issues.

Women are facing discrimination at work and even being forced out of their jobs because they haven’t got rights to take IVF treatment currently,” Aiken explains.

“It’s now come to the time that we’ve got to recognise IVF as a very, very important part of reproduction’ she says. “We’ve got an awful birth rate here in this country. We need to keep giving birth to children so that in 30 years’ time, they will be paying taxes, they will be our workers of the future.

“I would also like to see a legal requirement for employers to have a workplace fertility policy. I would like to see organisations introduce guidance on rights to time off work for treatment and miscarriage, flexible working, access to HR support and counselling on a confidential basis. This would help to improve workplace culture for workers looking to build a family through fertility treatment.”

Currently, legal safeguards against pregnancy-related discrimination only begin after implantation has taken place, so women often find themselves having to ‘hide’ the fact that they are undergoing IVF or try and arrange appointments outside of working hours, all of which will have an undeniable effect on stress levels.

Aiken will introduce a private member’s bill at the next parliamentary session to discuss IVF workplace discrimination.

The growth in fertility benefits

Although there is evidently a need to protect many women from IVF discrimination in the workplace, more and more companies are embracing the concept of extending fertility benefits to their employees.

Fertility benefits are proving a powerful way to attract and retain employees. In a survey carried out by Carrot Fertility, the leading global fertility benefits provider for employers, and The National Infertility Association, 88% of employees would even consider changing jobs for access to fertility benefits.

Aria Fertility is delighted to partner with Carrot Fertility to provide fertility care to their UK members.

Nutritional health does play a role in conception and pregnancy, yet there is so much conflicting advice online for those trying for a baby naturally, couples struggling with infertility or individuals experiencing health conditions that affect their fertility.

A fertility dietician can provide clear, personalised nutritional advice with regard to fertility, pregnancy and gynaecological concerns. The benefits can be wide ranging, including:

  • Optimising the chance of conception
  • Helping to regulate ovulation
  • Can improve egg and sperm health
  • May reduce the risk of miscarriage
  • May improve success rate of fertility treatments
  • Reduce pregnancy-related risk factors

Often just the act of focusing on diet can be good for allaying anxiety as the patient can feel they are being proactive at a time when so much is beyond their control.

Alex Ballard Fertility DieticianAlex Ballard (@alextalksdiet), a Band 7 specialist fertility dietitian in the NHS, specialises in preconception nutrition and works with Aria Fertility, helping patients with general enquiries about fertility and nutrition and how that links to fertility treatment or any other health conditions.

“I have been interested in the link between fertility and nutrition since I trained to be a dietician seven years ago as I had family members that were going through fertility treatment and friends that had been recently diagnosed with conditions such as PCOS and endometriosis.”

Unfortunately, it is often challenging to access this support through the NHS. “In seven years of working in the NHS, I have never had a patient referred to me who’s trying to conceive although I know there’s many that would benefit from it.

Support and advice from a fertility nutritionist can be accessed at any point in their journey, but Alex points out that there is optimal time to embark on any changes to lifestyle habits if you’re about to commence fertility treatment.

“If people are motivated then I can help at any stage in their fertility journey but there is a three-month cycle for eggs and sperm to mature to the point that they are ready for fertilisation so any changes you make consistently for 12 weeks or more is likely to have a really beneficial impact both on their fertility and then, hopefully, their pregnancy.”

Patients that could benefit from fertility nutrition advice

 “I see both couples and individuals and have three main types of clients,” fertility dietician Alex explains. “People at the beginning of their fertility journey are often looking for more general advice on a diet that is protective of fertility and foetal development.

“The second type of client has been trying to conceive for a long time and is about to start fertility treatment and wants advice specific for that.

“And, finally, I have many clients who have existing health conditions which are impacting their fertility, and which can be better managed through diet. This includes POCS, endometriosis, coeliac, Crohn’s, diabetes, or nutritional deficiencies.”

How does a fertility dietician work?

Although there is a lot of information available online, Alex finds patients are often overwhelmed and her role is to provide practical advice and workable plans that fit in with modern, busy lives.

“I’m always led by the client. The goal is always realistic, sustainable, and important to them. Just because I think something would be highly beneficial to them, if they don’t agree then it’s not going to be a sustainable change.

“I’m not going to send someone away with a long list of changes for them to implement. It’s more likely to be, let’s make one or two realistic goals and then touch base in a month or so and see how things are going.”

Final advice: variety and moderation are key!

“There are definitely foods that we know are particularly rich in nutrients and good for fertility, but the danger is that you can then fixate on some foods and not get enough of the other nutrients we need. I also advise patients not to be too extreme; never eliminate a specific food group, as every one has a purpose.”

We work closely with a wide range of practitioners to provide support throughout your fertility journey – click here to visit our Support Hub.

The latest UK statistics show that that half of women are now childless at the age of thirty for the first time since records began in the 1920s. A report from the Office for National Statistics (ONS) has found that 50.1% born in 1990 were still child free by their thirtieth. This follows the long-term trend of people opting to have children in later life and a smaller family.

The most common age to have a child is now 31. This is in direct contrast to baby boomers, born in the late 1940s, who were 22 on average when they began their families.

An explosion in opportunities for studying at university and pursuing careers was the catalyst for this trend and modern pressures such as the rising cost of childbearing and job uncertainty are also impacting the decision to start a family. But, at what cost to fertility?

Age affects fertility for both men and women, but in women it is the single biggest factor in determining whether you can conceive and carry a baby successfully. Fertility gradually declines in the 30s, particularly after the age of 35. Even before menopause, the ability to conceive naturally is unlikely by 45.

A woman is born with all the eggs she will ever have; at birth that is approximately 1 million eggs but, during your reproductive lifetime, only 300 to 400 will be ovulated and as you age, your eggs age and the number and quality reduces over time.

The decreased quality increases the chance of miscarriages, ectopic pregnancies and chromosomal abnormalities and raises the pregnancy risks. As you get older, you may also have other medical conditions that could affect your fertility.

Fertility treatment in my 40s: what are my options?

IVF treatment with PGT-A: For women in their late 30s and 40s that wish to undergo fertility treatment with their own eggs, we recommend screening all suitable embryos which have reached the blastocyst stage of development (day 5 embryo) using pre-implantation genetic testing for aneuploidy (chromosomal errors).

State-of-the-art embryo selection technology: Time-lapse imaging continuously monitors the development of the embryo and uses artificial intelligence, based on their developmental pattern, to identify the embryos which have the highest chance of implantation in the uterus.

Egg donation: Increasingly, egg donation is becoming a more effective way of overcoming age-related infertility. An egg donor may be anonymous or known to you and egg donation treatment is very similar to a standard approach to IVF, expect you will not be required to undergo the ovarian stimulation phase of the treatment.

If you are over 40 and would like to understand more about your own fertility, the first step would be to arrange a consultation to meet with one of our Aria consultants.