At Aria Laboratories, we are proud to be at the forefront of cutting-edge fertility research, constantly striving to push the boundaries of what is possible in the field of IVF. On Research Appreciation Day, a day dedicated to honouring the invaluable work of health researchers worldwide, we want to take this opportunity to celebrate the research being conducted at our laboratory.

Below are some research projects that we hope will shape the future of IVF with patient experience as a pivotal element:

Enhancing Non-Invasive Preimplantation Genetic Testing with Morphokinetic Data

One of our ongoing research focuses on utilising morphokinetic data to enhance the diagnostic precision of non-invasive preimplantation genetic testing (niPGT). niPGT involves the examination of markers on the culture media in which embryos grow, which is usually discarded.

This research aims to move towards a non-invasive genetic testing approach, eliminating the need for embryo biopsy. Encouragingly, this research has already resulted in live births, highlighting the safety and reliability of this non-invasive method. By embracing this innovative approach, we strive to minimise the invasiveness of genetic testing and optimise outcomes for our patients.

AI-Based Classification for Improved Sperm Selection

Understanding the maturity and integrity of sperm plays a crucial role in assisted reproductive technology (ART) procedures. To further our understanding in this area, we are conducting an analysis of single-sperm maturity using artificial intelligence (AI) imaging classification scores.

By harnessing the power of AI software, we aim to provide embryologists with a valuable tool that offers consistent second-hand opinions, aiding in the selection of the most viable sperm for ART procedures. This technology not only enhances the accuracy of sperm selection but also embraces the integration of new technologies in our IVF laboratory.

Semen Analysis with AI Robotics

Presented at the 39th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) in Copenhagen, this study explored how AI can improve andrology pathways while enhancing the overall patient experience.

By leveraging the power of AI robotics, we aim to streamline and optimise the semen analysis process, reducing turnaround time and enhancing accuracy. This research represents our commitment to embracing technological advancements to achieve the highest standards of patient care.

 

By collecting comprehensive data and insights, we aim to refine and improve our practices, ensuring the highest level of care and support for our patients throughout their fertility journey.

To find out more about the work of our embryologists, call +44 (0) 203 263 6025 or email us at admin@ariafertility.co.uk.

Following on from an international study published at the end of last year that demonstrated declining sperm counts are accelerating, new research has pinpointed that air pollution can significantly damage sperm quality.

A meta-analysis of nearly 27,00 studies identified factors such as air pollution, pesticide exposure, and chemical pollutants as causing increased sperm DNA fragmentation. The research was published in the journal Reproductive Biology and Endocrinology, and the studies they reviewed included data from men exposed to high levels of workplace pollution and those living in areas with high environmental pollution levels.

Standard male fertility tests check the number, motility and shape of the sperm. A further diagnostic assessment we offer at Aria Fertility is the sperm DNA fragmentation test. This provides more in-depth knowledge about sperm quality.

Sperm DNA fragmentation are breaks in the DNA strands that are contained within the sperm, and this can affect the ability to conceive and has been linked to a higher incidence of miscarriage. This is usually caused by oxidative stress and, as well as pollution, the study also identified several lifestyle factors that had a significant impact. Here are 5 common lifestyle factors that could affect male fertility.

Lifestyle factors and male infertility

1. Smoking

Nicotine addiction might be one of the most important lifestyle factors affecting fertility. Numerous studies have found smoking is associated with decreased sperm count, reduced sperm motility, and poor sperm morphology, which is how sperm are shaped, and in this most recent study, researchers demonstrated that smoking could increase DNA fragmentation by an average of 9.19 per cent compared to non-smokers.

2. Alcohol

How much is too much? Many studies have investigated the effect of excessive alcohol consumption and fertility and found that it impacts both male reproductive hormone production and the quality of your semen. One Danish study found that for men who consumed 40 units or more of alcohol per week, their sperm count was approximately 33% lower than those who drank between one and five units per week.

3 & 4. Your weight & diet

These two often go hand in hand. Generally speaking, men and women with a higher BMI are more likely to have lower fertility. Although it is not possible to say that losing weight will definitely improve your chance of conceiving, adopting healthy eating when trying for a baby is a sensible step. A healthy and varied diet, rich in vitamins and antioxidants, is essential for good sperm health.

5. Reduce your exposure to BPAs

Although it might not be possible to avoid the impact of environmental pollutants, particularly if you’re living in a large city, you can take steps to reduce your personal exposure to BPAs.

Bisphenol A (BPA) is one of the most common chemicals we’re exposed to in everyday life, as it’s used in everything from food and drink containers to dental fillings. Try to avoid canned food, use BPA-free plastic storage, eat fresh produce, cook from scratch, and use glass water bottles and reusable coffee mugs.

Call +44 (0) 203 263 6025 or email admin@ariafertility.co.uk to arrange a male fertility health check, including a sperm DNA fragmentation test, at Aria Fertility.

Fantastic news from one of our couples – we were delighted to be sent pictures of their twins and to hear the family were doing so well.

“Last year myself and my partner came to Aria after 2 failed IVF rounds elsewhere, where we unfortunately had no embryos to transfer. We were at our lowest point and Aria was our last chance of having our own biological children. Your team listened to us, were willing to consider and try different approaches, and for the first time didn’t make me feel like it was simply down to me being too old (now 40).

“With the help of your team we ended up with 6 blastocysts and transferred 2, which we were delighted resulted in our first ever positive pregnancy test, after years of trying.

“Last month, all the heartache and struggle finally became worth it and we welcomed our twin boys. Our hearts are so full and we can not thank the team at Aria enough for making all of our dreams come true. Without you our beautiful boys would not exist.

“Thank you to everyone who played a part, every person, every interaction and every decision made at Aria was worlds apart from anywhere else we have visited.”

To book a consultation with one of our fertility experts, call +44 (0) 203 263 6025 or email us at admin@ariafertility.co.uk.

In celebration of International Nurses Day, Maddy, who is egg donation coordinator at Aria, explains what drew her to working in fertility and the satisfaction she gets from being a fertility nurse.

What’s your favourite part about being a fertility nurse?

“The great thing about being a fertility nurse is the diversity of the day-to-day job. You can be down in theatre for the morning doing egg collections or looking after your patients in recovery. In the afternoon, you may be upstairs doing blood tests or scans or doing admin and following up with your patients with phone calls and emails.”

“Our appointments with our patients can cover talking them through their fertility treatment journey and what they can expect, explaining what their scans showed, or teaching them how to take their IVF medication.”

What element of your job do you find most special?

“I am the egg donation coordinator at Aria, which is really, really special. Everything is kept anonymous and takes careful planning to ensure that the donors and recipients are kept separate when they come in for their appointments. But it’s a special moment for both parties, and often the recipients come in with a gift or card for their donors. It’s lovely to see their kind words, and it always reminds me why I am doing this job in the first place.

“We use an external donor organisation that recruits the donors, and then we match them with our patients who may have experienced failed cycle after failed cycle and are unable to use their own eggs.

“I oversee the whole process, so I work with the donor from start to finish, doing their consent forms, blood tests, etc. And then I organise the recipients.”

What makes working in a fertility clinic different to other sectors of nursing?

“The continuity of care and hands-on nature of the role is critical. You see patients throughout an intense journey and are there for their outcomes, whether it’s egg freezing or they are creating embryos. Once they become pregnant, we see them up until 12 weeks before they move to antenatal care with their local hospital or private obstetrician.”

What makes working at Aria Fertility special?

“The team at Aria have all been together since it opened – the doctors, nurses, and the admin team – and we’ve created something unique.

“We are also a small team, so you often look after patients at every stage of their journey. We have a lot of egg-freezing patients at Aria Fertility. The initial step is a consultation with their doctor; then they will have a nursing consultation which I do many of. This will be quite a lengthy appointment as we explain the process thoroughly. You see them for their scans and track their follicle development, and then you often see them on the day of their egg collection.

“Today, we said farewell to one of our egg-freezing patients, who has done a couple of rounds and banked enough eggs. And hopefully, we may see her again in the future!”

What made you specialise in fertility nursing?

“My background is in theatre recovery nursing. I moved here from Australia in 2016 and initially did agency nursing, working at hospitals around London. My recruiter contacted me with a month-long temporary position at a fertility clinic; it’s always lovely to have longer-term positions as an agency nurse, so I immediately said yes. And, from the moment I stepped in the door, it was love at first sight.”

What’s the next stage for you in fertility nursing?

“If any area of nursing needs spotlighting, its fertility nursing. People often think you need lots of experience or training, but you learn on the job, and there’s endless progression.

“I started with zero experience, and five years later, I’m now donation coordinator and furthering my knowledge of scanning. I currently do follicle-tracking scans, and next week I’m doing a scanning training course for two days, so in the future I’ll be able to do pregnancy and diagnostic scans.

“After your initial consultation with our doctors, you’ll have a fertility check, and a diagnostic scan is a cool 3D scan of the uterus to identify any potential issues such as cysts or fibroids. I’m very excited about this next stage!”

April is Stress Awareness Month and although most of us can manage small amounts of stress – which can even help you focus on achieving short-term goals – chronic stress can eventually affect how you cope with daily life. And, the longer stress lasts, it can even become a threat to your health and wellbeing.

Long-term stimulation of the stress response system means we’re overexposed to cortisol and other stress hormones, and this can lead to mental health problems, insomnia, digestive issues, muscle tension, cardiovascular disease, high blood pressure, stroke, and cognitive impairment.

It is not fully understood how stress affects fertility. Some studies have shown adverse effects, while others don’t, and most are only small-scale studies at this stage. We certainly know that the reverse is true and struggling to conceive can be very stressful. One study published in the Fertility and Sterility Journal surveyed 352 women seeking treatment for infertility and found that more than half of them showed signs of depression and three in four showed signs of anxiety.

So, whether your stress is related to your struggles conceiving or other factors, how does it affect your fertility and pregnancy outcomes?

Stress and your fertility

Stress triggers the body’s fight or flight response. In short, this means releasing stress hormones like cortisol which have an immediate physical impact such as increased heart rate, shallow breathing, high blood pressure and stress headaches.

When you are experiencing a prolonged period of extreme stress, the body will shut down any systems that it does not deem necessary for survival. This is why you can experience hair thinning a few months after a very stressful situation – telogen effluvium is a type of hair loss that results from an interruption in the normal hair growth cycle. In terms of your fertility, this can cause delayed or absent ovulation and irregular or missed periods.

In one small-scale study from 2015, women in the high stress group based on perceived stress assessments were found to have lower levels of oestrogen, progesterone and luteinising hormone. They also had higher levels of follicle-stimulating hormone during a particular stage of their cycles which meant an increased chance of anovulation which is when an egg is released from the ovary during your menstrual cycle. Chronic anovulation is a common cause of infertility.

[ext link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315337/]

Another key stress hormone, CRH or corticotrophin-releasing hormone, is present in diseases that cause inflammation. Abnormal levels of CRH can affect the uterine lining and placenta and therefore could adversely affect implantation.

However, not every study has found a link and 2019 investigation found no difference in conception rates in women based on their daily reported perceived stress levels and a 2017 study of women undergoing IVF concluded that perceived stress and high cortisol levels “were not associated with IVF cycle outcomes”.

Managing stress during IVF

At Aria Fertility, we know how important it is to find ways to manage your stress throughout your fertility journey. Our doctors, nurses and embryology team provide comprehensive patient care combined with a wealth of medical experience and expertise, so you know you are in the best possible hands.

In our Support Hub, we have brought together organisations and individuals that offer fertility support, advice and information. Methods for managing stress encompass counselling, acupuncture, reflexology, and nutritional support.

For more advice on managing stress during your fertility journey, call +44 (0) 203 263 6025 to arrange a consultation.

The Human Fertilisation and Embryology Authority (HFEA) has opened a patient consultation process regarding proposed changes to UK fertility laws which they say are inflexible and not reflective of modern fertility practice.

The Human Fertilisation & Embryology Act (HFE Act), the law that currently governs fertility treatment and embryo research in the UK is over 30 years old. The HFEA believe that it no longer accurately reflects the medical and scientific innovations and changes in societal expectation that have occurred over the subsequent decades. They recommend sweeping reforms, proposing to put patients at the heart of fertility law.

Julia Chain, Chair of the Human Fertilisation & Embryology Authority (HFEA), explains: “Much of the fertility law has stood the test of time remarkably well but modern fertility practice, emerging possibilities in research that could benefit patients and the changing expectations of donors and of families, are not reflected in the sector’s 30-year-old law.

“With input from an expert advisory group, we have identified where the law needs to be modernised in the interests of patients and their families. This includes providing more up to date powers for inspecting and regulating fertility clinics in the interests of patients and greater choice around donor anonymity. However, it’s important to note that any decision to update the law is for the Government and ultimately Parliament to decide.”

Fertility law changes being considered

  • Changes to HFEA’s regulatory powers so they can more rapidly impose conditions, suspend all, or part of a service for a specific period of time, or impose financial penalties where there have been serious non-compliances
  • Extending HFEA’s powers to address fertility services outside licensed fertility clinics
  • Changing current access to donor information, including providing parental and donor choice where they can opt for anonymity until age 18 (as now) or identifiable information on request after the birth of a child.
  • Allowing automatic record-sharing between fertility clinics and GPs to ensure safer patient care.
  • Encouraging innovation by allowing the HFEA to authorise trials for low-risk new practices.

HFEA also plan to future proof the law to ensure it is better able to respond to scientific developments and speed up potential new treatment options for patients.

Since the Human Fertilisation and Embryology Act was established in 1990, fertility care in the UK has changed rapidly and currently around 60,000 patients use fertility services every year and approximately 60% of them will pay for their own treatment.

The HFEA consultation opened on 28 February and will run for six weeks on the regulator’s website. It will submit its recommendations for law changes to the Department for Health and Social Care by the end of the year.

For more information and to share your views, Fertility Network UK are holding a webinar on the HFEA’s proposed changes to fertility law with Peter Thompson from the HFEA. The webinar will explain more about this consultation process, what the proposed changes mean to patients and how patients can get involved.

You can register here: Webinar – Why Changes To Fertility Regulations Matter To You | Fertility Network

Infertility affects an estimated 15% of couples globally and in approximately half of those couples experiencing difficulties conceiving, part of the problem will lie with the male. However, the burden of fertility treatment still resides mainly with women. The perception that assisted reproductive technology, particularly Intracytoplasmic sperm injection (ICSI), has ‘solved’ male fertility means that male infertility research has often been neglected.

However, as leading fertility nutritionist Melanie Brown believes, a shift in thinking about male infertility could greatly improve treatment outcomes or even increase the chance of natural conception.

“Often men feel, or are even told, that if they have poor quality sperm, there is nothing they can do about it. But that’s just not the case.”

Melanie has an MSc in Nutritional Medicine and over twenty years of working in fertility and preconception nutrition, and she is especially interested in supporting male infertility.

“The focus is almost exclusively on women and their fertility, but intervention should probably come with men when they are at school. Young men should be given more nutritional and lifestyle education about protecting their fertility in their late teens and 20s.

“Obesity, for example, isn’t always an open and shut case as it doesn’t account for diet. You may have an obese man eating a very rich, indulgent diet with too much red wine, pasta and potatoes, but it is also a varied diet, and he’s still consuming his vegetables and olive oil. On the other hand, you can have an obese man just eating lots of beige, ultra-processed fast food, which is very bad for sperm quality.”

The pursuit of perfection and fertility

In an ironic twist, known as the Mossman-Pacey paradox after the two UK scientists that discovered it, the human male is seemingly the only species that make themselves less fertile while trying to look more attractive to the opposite sex.

“Lifestyle changes in recent years have been disastrous for sperm quality,” Melanie explains. “For example, lots of young men are now using hair growth medication to halt male pattern baldness, and these products are now readily available and heavily promoted. But they can be very damaging for sperm.

“Steroid use is also becoming a significant problem for many young men, which could actually finish off their testicles for good! Even protein powders contribute as they can contain a minimal amount of steroids.”

And this focus on women over their male counterparts extends throughout the fertility treatment journey. “My thesis was on the impact male obesity has on IVF outcomes as there is so much research into female obesity and women being told they must be a specific BMI for IVF, but male BMI is not considered. Furthermore, most men don’t even have their testicles examined before IVF to check if they have a varicocele or if they look slightly smaller than normal, whereas women are prodded and poked endlessly with examinations.

“Often, this is because ICSI allows men to circumvent specific issues. If it’s left further down the fertility treatment pathway, it’s too late, but the fact is that a good diet and lifestyle changes can help sperm.”

Lifestyle factors and male infertility

Pollution may be a big factor; a Danish study published last year looking at pollutants, including BPA, in semen and their relationship with deteriorating sperm quality found that the men aged between 20-30 in their study had up to 100 times the safe limit of various pollutants and this correlated with their sperm quality.

“There are some steps you can take to mitigate exposure to these harmful chemicals, such as using a BPA-free drinking bottle, never heating your food in plastic, eating some organic foods – look at The Dirty Dozen and the Clean Fifteen lists on the internet – and avoiding parabens in toiletries.

“Covid has also played a role. There has been a drop in activity levels since the pandemic, but exercise is critical for testosterone metabolism. Although it has to be the right exercise: cycling is fine but respect your testicles!

“Nutrition is the big one, though. I find a lot of my research from animal studies, as vets and farmers know how valuable sperm is – you wouldn’t believe how much money a vial of good bull sperm costs now! Breeding animals have the best nutrition to ensure high-quality sperm, but this research hasn’t been extrapolated to the human male.”

Small steps to make significant changes

Melanie explains how she typically works with male clients. “I see very few men who come off their own bat – usually, they are part of a couple or referred by urologists I work closely with.

“I explain that it’s a 12-week project – as that’s how long it takes sperm to regenerate – and set them strategies and goals, and then they are typically highly motivated.

“It’s often about making tweaks – small or large – to their regular diet and routine. So, breakfast may remain the same, but I advise them to add some berries. If they don’t want to take a packed lunch to work, I might say go to Pret rather than Subway, choose a sandwich with egg, avocado or rocket, and opt for nuts rather than crisps. The basis of a good sperm diet is The Mediterranean Diet, full of fresh colourful un-processed foods. I also recommend some carefully selected supplements. However, too many supplements at too high amounts can also be very bad for sperm. Diet is key.

Male infertility can often be an isolating experience, so this is an opportunity for teamwork. “If you present as an infertility couple, the emphasis shouldn’t be on who’s at fault. Making these important changes to improve sperm and egg quality before fertility treatment can be a great bonding experience before you move to the next stage.

Fertility Nutritionist“Male infertility is often the canary in the coal mine for men’s health,” Mel believes. “If there are infertility problems, then a bigger issue should probably be addressed.”

For more advice on anything fertility and nutrition-related, contact Mel directly to make an appointment or to find out more. Call +44 (0) 203 263 6025 or email us on admin@ariafertility.co.uk for advice on male infertility treatments.

For more information on the individual practitioners and organisations offering support, advice, and information to those undergoing fertility treatment, please visit our Support Hub.

Chinese Medicine theory is based on the healthy functioning of the body being governed by the flow of Qi (or energy) through a system of channels (or meridians) under the skin. When this flow of Qi becomes blocked, illness occurs. When acupuncture is performed, fine needles are inserted at various points along the channels and the body’s balance can be restored and the illness is resolved.

We invited Melanie Hackwell of Ancient Roots Fertility Acupuncture to answer your questions and explain why you may want to consider acupuncture as a complementary therapy when starting your fertility journey.

“I only practice acupuncture for Fertility and Women’s Health. I have been practicing this speciality for 10 years and hold a BSc in Acupuncture, as well as receiving clinical training in China, and extensive post-graduate training in Fertility for both female and male. I am currently working on my Advanced Level Diploma in Fertility Acupuncture.”

What will happen at my first session?

“Your practitioner will conduct a detailed case history of the patient using Chinese Medicine theory, in order to gain background into how the illness arose, what patterns are evident, looking at the tongue and take the pulse, and make a diagnosis.

“Based on that diagnosis, they will put a set of acupuncture points together to use to assist with restoring health and balance to the patient. They may also use a herb called moxa to warm a certain area of the patient’s body and will also make various lifestyle and diet suggestions.”

Does Fertility Acupuncture hurt?

“When done correctly it does not hurt but the patient may feel a sensation such as a dull ache.”

Are there any side effects?

“There may occasionally be some bruising in certain areas, or the patient may feel tired after treatment (especially with the first treatment). This does not last long, and the patient normally feels refreshed a day or two days after treatment.”

How many sessions will I need?

“This is a question that is very difficult to answer until a detailed case history is conducted and the practitioner sees how the patient responds. I generally tell patients that I need about three months to clear any underlying issues that I can see.”

When should I start acupuncture for IVF?

“In order to have the best results, I will need to see you regularly for a period of months. I will often have people approach me a week before starting fertility treatment. While I am happy to help and the acupuncture will provide relief from the stress that a patient is under, more time is required to clear the underlying issues that I see so often in clinic and to work on egg quality and/or semen quality.”

What can I expect from Fertility Acupuncture?

“One of the most important aspects to be aware of is that I was once sitting where you are today. I am fully versed with the pain and intense emotions that go along with trying to conceive. A large amount of empathy is given to my patients which I feel is essential in the healing process.

“Like all acupuncturists, I will conduct a detailed case history. However, with Fertility Acupuncture I will also delve into the immune system in great detail along with any previous illnesses one may have experienced.  I will also be looking at lifestyle, and ask for certain tests to be conducted such as thyroid and vaginal microbiome.  By the time you have visited an IVF clinic, you will have already had all of your hormone levels tested so we will be looking at those as well.

“Increasingly, due to various environmental factors, I am seeing more and more men requiring treatment and we will be investigating that side of things also.

“I will give you an honest opinion of how long I feel treatment will be required. I do however ask that you give me time to tackle the underlying issues that I see on a daily basis.

Fertility Acupuncturist“I am delighted to have a chat with anyone who needs more information or just so we get to know one another. I feel it is so important to build a close relationship to my patients, so they trust in the support and advice that I give them.”

Contact Melanie directly to make an appointment or to find out more. For more information on the individual practitioners and organisations offering support, advice, and information to those undergoing fertility treatment, please visit our Support Hub.

Since Jennifer Aniston opened up about her own experiences with IVF and expressed her regret that she had not undergone egg freezing earlier, even more women have begun exploring their fertility preservation options.

Women now have the option of freezing their eggs or embryos, but there are critical differences between the treatments that can determine the best choice for them.

The collection stage

Both procedures start with the same basic premise of egg collection. You will self-administer hormone injections, stimulating the ovaries to produce mature eggs over 8 to 12 days. We will monitor your progress during this stage, and your eggs will be collected at the optimal time. This is a minor surgical procedure performed under sedation in the clinic. The collected eggs are then transferred to our laboratory.

To fertilise or not fertilise

This is the crucial difference between the two treatments. Before they are frozen, the eggs can be fertilised in our laboratory using either your partner’s sperm or donor sperm.

This takes place on the same day as the egg collection. Our embryologist will try to fertilise all mature eggs using intracytoplasmic sperm injection, or ICSI. If successful, the fertilised eggs will develop into an embryo. Over the next five to six days, the embryos will be carefully monitored as they hopefully progress to the blastocyst stage. The embryos that successfully develop to this stage are then frozen.

The freezing and storage process

Both eggs and embryos are frozen and stored using a method known as cryopreservation. Water in the cell is replaced with a freezing solution called a cryoprotectant which prevents this water from crystallising in the freezing process. The freezing process is called vitrification and entails flash freezing, instantaneous cooling from 37oC to -196oC. The eggs or embryos are then stored in liquid nitrogen.

Using your embryos or eggs

When you’re ready to use your embryos or eggs, our embryologist will thaw them. An embryo that has successfully thawed can be transferred directly back into the body. Frozen eggs that survive the thawing process will then be injected with a partner or donor’s sperm to fertilise them. The fertilised eggs will then develop into embryos and after five to six days can then be transferred to the womb.

The pros and cons of egg freezing vs freezing embryos

Previously, slow-freezing technology was used to freeze eggs or embryos. The cells were cooled very slowly over a couple of hours to avoid ice crystallisation until they reached the optimal storage temperature. Embryos were thought to survive the freezing and thawing process better than eggs as the latter are large size cells with a high-water content, so they are more susceptible to ice crystals forming and causing cellular damage.

The introduction of vitrification or flash freezing has largely eliminated this difference, and the survival rates when freezing eggs versus embryos are now very similar.

Choosing to freeze embryos means you have more information on how many eggs were healthy enough to fertilise and begin development. However, the most important difference is that freezing eggs rather than embryos grants women reproductive autonomy, giving them more options in the future.

Aria Fertility Counselling

Discussing your treatment choice with one of our counsellors can be a very rewarding and empowering session. At Aria, we wish for everyone undergoing fertility preservation treatment to have a full understanding of choices they are making and implications these may have for the future. Our wonderful counsellors will always be able to spare time to have a chat with you and help you come to a decision if you feel you require their expert support.

If you have more questions about our fertility preservation options, call +44 (0) 203 263 6025 or email admin@ariafertility.co.uk to arrange a consultation with one of our fertility specialists.

For years, the media has speculated on Jennifer Aniston’s ‘choice’ not to have children and now she has finally shared the truth about her struggles with IVF and trying to conceive.

In an interview published in Allure this month, she spoke candidly about her attempts to get pregnant with IVF during her late 30s and 40s.

“I was trying to get pregnant. It was a challenging road for me, the baby-making road,” she said.

“All the years and years and years of speculation… It was really hard. I was going through IVF, drinking Chinese teas, you name it. I was throwing everything at it.”

Jennifer also revealed that she wished that someone had advised her to freeze her eggs at an earlier age: “I would’ve given anything if someone had said to me: ‘Freeze your eggs. Do yourself a favour.’ You just don’t think it. So here I am today. The ship has sailed.”

So, why is your age such an important when it comes to egg freezing?

A study carried out by Imperial College London researchers published earlier this year found that women who freeze their eggs at 40 are unlikely to have a successful live birth. This supports the advice from Human Fertilisation & Embryology Authority (HFEA) that age is the key factor in egg freezing success.

The Imperial College London study suggested that women should be encouraged to undergo elective oocyte cryopreservation, commonly known as egg freezing, before the age of 36 to mitigate age-related fertility decline.

Egg freezing is becoming more and more popular as a fertility preservation and the results from the UK study suggest women should be encouraged to undergo egg freezing much earlier than the evidence suggests they are currently doing.

Egg freezing FAQs:

  1. What is the best age to freeze your eggs?

Fertility begins to decline from the age of 35, this decline becomes more rapid once you reach your mid-30s and so your optimum age to freeze your eggs would be your late 20s and early 30s.

  1. What happens during the egg freezing process?

Our fertility nurses are on hand to take you through the whole process. This usually starts with hormonal injections on day two of your cycle for approximately two weeks. We will carry out regular scans to monitor your progress and, when the follicles have reached the right stage of development, we give you a trigger injection to encourage final maturation of the eggs within the follicles.

Egg collection is then scheduled 36-38 hours later. This is a minor surgical procedure lasting between 20 and 30 minutes, carried out under intravenous sedation. The eggs are checked and then frozen and stored for your use in the future.

  1. How long can my eggs be stored?

Previously, eggs, sperm or embryos could only be stored for up to ten years except in cases of premature infertility or if undergoing medical treatment which could affect fertility. On 1 July 2022, these rules changed and now the law permits you to store eggs, sperm or embryos for up to 55 years, although you need to renew your consent every ten years.

If you have more questions about egg freezing and our success rates, call +44 (0) 203 263 6025 or email admin@ariafertility.co.uk to arrange a consultation with one of our fertility specialists.