Endometriosis can raise a lot of questions, especially when it comes to fertility. Recently, Carla Cressy of The Endometriosis Foundation sat down with Aria Fertility’s Ms Srividya Seshadri to discuss the link between endometriosis and fertility.

Carla: We’re sitting down with gynaecologist and fertility specialist, Ms Srividya Seshadri at Aria, where we’ll be talking openly and honestly about what endometriosis really means for reproductive health. We’ll cover everything from lifestyle and early testing to fertility preservation treatments and planning a pregnancy so that you can feel informed, supported and empowered to make decisions that are right for you at the right time. Before we talk about medical treatments or fertility preservation. I wanted to start with something a little more fundamental, like the everyday things that people can do to support their fertility.

How do nutrition, stress and sleep play a role in long -term fertility, especially for those with endometriosis?

Vidya: You’ve highlighted two very important factors that could affect fertility. Recently, there has been a focus on PFAS, or forever chemicals, and their potential effects on egg and even sperm quality.

I’m a big believer that nutrition should be in pristine health, at least before any fertility treatment is contemplated. This can range from diet, what triggers to avoid, or curbing excessive caffeine or alcohol intake

Vitamins are also important for fertility, especially folic acid. Folic acid is paramount for egg quality and early pregnancy development, especially the central nervous system development of the baby. Vitamin D also plays a powerful anti-inflammatory role, and we should really be taking it year-round.

One of our government’s guidelines is that all of us who live in the UK must take a daily dose of 10 micrograms of vitamin D. It’s not only helpful during the Winter, but it’s also very good for symptoms of endometriosis and improving egg quality.

However, anything taken in excess is also not great for egg quality. Vitamin E is thought to be good for the eyes and the skin. But it’s a fat-soluble vitamin and so is stored in our fat deposits for a considerable length of time.  Also, taking too much vitamin A in early pregnancy is not conducive to embryonic growth and could be quite toxic for early embryo development. So, I would say avoid vitamin A if you’re trying to conceive.

Sleep is also very important, and we often underestimate its effect on egg quality. There have been some observational studies in the US that looked at how sleep quality affects egg quality, and I’m a firm believer that we need everything in balance to achieve an optimum outcome.

Carla: What fertility tests are available for someone with endometriosis, even if they’re not trying to conceive yet?

Vidya: The fertility investigations would include a blood test that checks our Anti-Mullerian Hormone level. It’s a hormone secreted by small cells lining the follicle, or fluid bubble, that contains our eggs.

It gives us a rough indication of our egg reserve at a given point in time compared to that of a woman of our age. But it does not often predict your future fertility.

So, if you’re an individual wanting to exercise your reproductive choice or even have underlying endometriosis and considering fertility preservation, then doing that test may be valuable because then you can ascertain if you want to do an IVF cycle for egg freezing before embarking on endometriosis treatment.

The test is not dependent on your cycle, so it can be done at any point in your menstrual cycle. The second test is a transvaginal or internal scan.

For individuals with endometriosis, this scan will be very important because endometriosis often causes scarring due to inflammatory deposits or adhesions. A transvaginal scan will also ascertain the position of the ovaries and the number of follicles.

As I alluded to earlier, follicles are the bubbles that contain eggs, so they represent the number of eggs recruited from the federal egg bank reserve each month.

Those are the two tests I would initially offer. But doing tests just for the sake of checking things without wanting to do anything about them is not advisable. But I tell any patient, it is valuable to ensure that our diet, exercise, nutrition, and supplements are in order. Those are the parameters I would look for or try to optimise before we start thinking about reproduction.

Carla: When should someone with endometriosis consider having fertility preservation?

Vidya: If they have been diagnosed with stage 3 to stage 4 endometriosis, and they’ve done their AMH level, and it is borderline.

I feel strongly that the number doesn’t always matter because I have seen individuals with severe endometriosis with a very good AMH value, but I still would encourage them to consider egg or embryo freezing because of the nature of the condition.

The reason for that is that endometriosis is a very difficult condition to predict. Unfortunately, we cannot map out the reproductive cycle and tell an individual how many months they have before their AMH or egg reserve drops. And with endometriosis, that drop could be quite sudden, from a very good egg reserve to negligible.

So, a blood test should not explicitly dictate what an individual should do.

Carla: At what point should someone with endometriosis who is actively trying to get pregnant seek help?

Vidya: I believe that after three to six months of trying naturally, if there is no natural conception, they should seek medical investigations and further intervention.

Now, saying that, not all women with endometriosis have difficulty conceiving. There have been many anecdotal cases where women have had severe endometriosis and have fallen pregnant naturally and have had a wonderful pregnancy and child delivery.

So, I don’t think we need to sort of compartmentalise based on the severity of the diagnosis, but it would depend on the individual’s symptoms, what stage they are at in their life, and their individual circumstances before they make that decision.

Carla: How do you help patients to understand results without any unnecessary fear or anxiety?

Vidya: That is a very important question because, as a clinician, conveying a test result without causing undue anxiety for the patient is paramount. And often it’s difficult because what they take home from the discussion about the results may be completely different from what the clinician discussed with them.

I discuss their results with them, give them time to reflect on the discussion and, if they want, have a follow-up appointment so they can ask any questions that have been left unanswered or help with any ambiguity in their decision-making.

Carla: One of the most common and often kind of frightening beliefs around endometriosis is that it automatically means infertility. What is the real link between endometriosis and infertility?

Vidya: Very good question. The link between endometriosis and infertility is not clearly defined, but up to nearly 50 % of women with endometriosis have problems conceiving. It is a lot, but again, we must bear in mind the other side of the coin that the majority have no problem conceiving.

But endometriosis is an inflammatory condition; those deposits, as they travel through the tubes, can cause scarring and therefore tubal blockage, preventing the egg from fertilising the sperm. Or it could mean that these deposits sit in the ovaries and are akin to rust on metal.

And this inflammation of the ovaries can mean that egg numbers and egg quality can rapidly deteriorate.

Carla: And what do the actual statistics tell us versus the myths that we often hear?

Vidya: The myth we often hear is that if you’ve got endometriosis, you can’t conceive, and you’re doomed for infertility, or you can only conceive through IVF treatment, and the answer is no, because most women with endometriosis have no problem conceiving.

Another myth is that if you get pregnant, be it through natural conception or IVF, your endometriosis will improve. That is a myth that’s been busted. Some women can have a smooth pregnancy, but quite often symptoms will return shortly after birth; for others, their pain just exacerbates during pregnancy.

What I don’t want is for everyone to panic about being diagnosed with endometriosis, because number one, we have so much more information compared to 25 years ago.

For more advice on how we treat patients with endometriosis, please arrange an initial consultation with one of our fertility experts.

When you are trying to conceive, it is natural to focus on the obvious things: your diet, your cycle, your supplements. Sleep, by contrast, tends to get overlooked. It is easy to dismiss a few disturbed nights as an inevitable side effect of anxiety and hope rather than something that meaningfully affects your chances of becoming pregnant.

But a growing body of research suggests that the relationship between sleep and fertility runs far deeper than most people realise, and that prioritising rest may be one of the most valuable things you can do for your reproductive health.

Today is World Sleep Day, an annual global awareness event that highlights the critical importance of sleep to our health. Here, we look at the relationship between sleep and IVF outcomes and whether better sleep could improve your fertility.

Why sleep matters for hormones and fertility

Sleep is not passive. While you rest, your body is carrying out an enormous amount of hormonal work, and many of the hormones that regulate your reproductive system are directly tied to your sleep-wake cycle.

Oestrogen, progesterone, luteinising hormone (LH), and follicle-stimulating hormone (FSH) all follow circadian rhythms, meaning they rise and fall in patterns anchored to light, darkness, and sleep. When those patterns are disrupted, our hormones can follow suit.

Central to this process is melatonin, the hormone produced by the pineal gland in response to darkness. Most of us think of melatonin simply as a sleep signal, but it plays a much broader role in female reproductive health.

Research published in Fertility and Sterility found that melatonin acts as a powerful antioxidant within the follicular fluid surrounding developing eggs, protecting oocytes from oxidative stress at the vulnerable moment of ovulation. Disrupting the regular production of melatonin through poor sleep, irregular sleep patterns, or excessive evening blue light exposure may therefore have a direct impact on egg quality.

Recent research in Frontiers in Endocrinology further highlights that disturbances to the circadian system, such as those experienced by shift workers, are associated with disrupted menstrual cycles, underscoring how tightly reproductive hormones are tied to our internal body clock.

What the research tells us about sleep and IVF outcomes

For those preparing for or undergoing IVF or ICSI treatment, the evidence around sleep is particularly compelling. A 2025 prospective cohort study published in the journal Sleep found that women reporting poor sleep quality had significantly fewer retrieved and mature oocytes compared with women who slept well. Difficulty falling asleep more than three times per week was also associated with fewer good-quality embryos. The researchers concluded that optimising sleep patterns holds real promise for improving IVF outcomes.

A separate study of women undergoing IVF or ICSI, published in Human Reproduction, found that sleeping fewer than seven hours per night was associated with reductions in both the number of eggs retrieved and their maturity.

Interestingly, the timing of sleep also appeared to matter, with mid-sleep times that were either too early or too late linked to lower fertilisation rates. The sweet spot, both studies suggest, is somewhere between seven and eight hours of good-quality, well-timed sleep each night.

Preconception planning: getting your body ready

Whether you are in the early stages of trying to conceive naturally or preparing for fertility treatment, the months before you begin are a remarkable window of opportunity. The eggs that will be retrieved or ovulated in the coming weeks and months are being matured right now, and the environment your body creates during that time matters. Sleep is one part of that picture, alongside nutrition, movement, and emotional wellbeing, but it is one that is often underestimated.

Consistent, restorative sleep supports healthy cortisol patterns, reduces systemic inflammation, and keeps the hormonal axis that governs your cycle in better balance.

Conversely, chronic sleep deprivation elevates cortisol, which can suppress GnRH and interfere with the downstream hormones that drive ovulation. You do not need to be suffering from a recognised sleep disorder for disrupted sleep to have an effect; the cumulative impact of regularly cut-short nights or poor sleep quality can quietly undermine your hormonal health over time.

Simple steps can make a real difference:

  • Keeping a consistent sleep and wake time
  • Reducing screen exposure in the hour before bed
  • Making your bedroom cool and dark
  • Limiting caffeine after midday
  • Look to your diet as certain foods can either promote or inhibit sleep
  • Keep fit and active

Approaching IVF in optimal health

For couples and individuals preparing for IVF, it is worth thinking about sleep as part of the broader preconception health picture rather than something separate from it.

Being in optimal health before you begin treatment does not mean being perfect. It means giving your body the best possible conditions in which to respond. For most people, that includes eating well, moving regularly, managing stress, being at a healthy weight, and yes, sleeping enough.

If you would like to explore how best to prepare for fertility treatment, arrange an appointment with one of our experts to discuss preconception planning and organise an assessment for a clearer picture of your fertility health.

Yesterday, Aria’s Srividya Seshadri and Zoe Webb attended a panel held at the Houses of Parliament in aid of Endometriosis Awareness & Action Day. Hosted by Carla Cressy of The Endometriosis Foundation, the inspiring event was dedicated to crushing the taboo surrounding endometriosis.

Dr Seshadri spoke on the panel about the link between endometriosis and fertility and what we can do to help patients:

“It was an honour to join the panel of experts to discuss this often distressing disease. I believe in the four Es of endometriosis. First, it’s essential to educate everyone about this condition. We should also encourage individuals to discuss its impact on them. Then empower them to make informed decisions about their reproductive choices. Lastly, help them evolve into an endometriosis warrior!”

Aria team attend Endometriosis Awareness Event

Aria’s theatre manager, Zoe, herself suffers from endometriosis and was honoured to attend both on a professional and personal level. “It was incredibly inspiring to hear such courageous and vulnerable stories as well as listen to the top experts in the field of endometriosis and fertility, which included Aria’s Dr Seshadri. We have a long way to go in the fight for better endometriosis care, but today reminded me exactly why we keep going.”

For more advice on your reproductive choices if suffering from endometriosis, get in touch to arrange a consultation with one of our fertility experts.

Many people expect that once you’ve had a child, having another one should be straightforward. Secondary infertility can feel deeply frustrating when you had expected a second pregnancy to happen easily. It’s also surprisingly common, affecting approximately 5% of the UK population.

At Aria Fertility, we support many individuals and couples facing this situation.

What is secondary infertility?

Secondary infertility is described as difficulty conceiving or carrying a pregnancy after you have already had one or more pregnancies. As with primary infertility, the NHS defines secondary infertility as not getting pregnant after 12 months of regular unprotected intercourse, or after six months if you are over 35 or there are known risk factors.

Unfortunately, for many, secondary infertility carries a distinct, often overlooked social stigma, in which they feel their experience is minimised because they already have a child. It’s often accompanied by complex emotions, particularly guilt and shame.

Why does secondary infertility happen?

Age is one of the most important factors. As maternal age increases, egg number and quality decline, which reduces the chance of natural conception and increases the risk of miscarriage. In the UK, people are starting families later, and data show that those becoming parents at older ages are more likely to experience infertility.

Other causes often mirror those seen in primary infertility. Ovulatory disorders such as polycystic ovary syndrome, tubal damage after pelvic inflammatory disease or previous surgery, endometriosis, fibroids and uterine adhesions can all contribute.

Male factor issues, including reduced sperm count or motility, are present in a substantial proportion of couples and may have developed since the previous pregnancy.

Lifestyle factors such as obesity, smoking and excessive alcohol intake, as well as medical conditions that arise between pregnancies, can further increase the risk.

When to seek help

National guidance recommends referral for specialist fertility assessment if you have not conceived after one year of regular unprotected intercourse. Earlier referral is appropriate if you are 36 or over, have known conditions such as irregular ovulation, endometriosis or previous pelvic infection, or if your partner has known sperm problems.

If your menstrual cycle has changed significantly since your last pregnancy, if you have pelvic pain, very heavy or irregular periods, or a history of miscarriage, it is sensible to seek advice sooner.

We also encourage you to reach out early if the emotional toll is becoming overwhelming; psychological distress is common among those experiencing infertility.

How secondary infertility is assessed

A fertility workup for secondary infertility follows similar principles to assessment for primary infertility, but we will pay particular attention to any changes since your last pregnancy. We begin with a detailed medical, reproductive and lifestyle history for both partners, including information about your previous pregnancy, delivery and any complications.

Investigations typically include blood tests to assess ovulation and ovarian reserve, such as follicle-stimulating hormone, anti-Müllerian hormone and mid-luteal progesterone.

A pelvic ultrasound helps us evaluate the uterus and ovaries and can detect conditions such as fibroids or ovarian cysts, while further tests, such as hysteroscopy, may be used to treat polyps or adhesions if suspected.

For tubal assessment, procedures such as hysterosalpingography or HyCoSy can check whether the fallopian tubes are open. A semen analysis is essential to evaluate sperm count, motility and morphology and to guide treatment options.

Treatment options and next steps

Your treatment plan will be tailored to the underlying cause, your age and how long you have been trying to conceive. For some, targeted lifestyle changes, weight optimisation, smoking cessation and timed intercourse guided by ovulation tracking may be enough to improve the chances of conception. When ovulation is irregular, medications to induce or regulate ovulation can be highly effective, especially in conditions such as polycystic ovary syndrome.

If sperm parameters are mildly affected or there are unexplained factors, intrauterine insemination may be offered. A large UK observational study has shown that while IVF has higher live birth rates per cycle than IUI, the difference is smaller than previously thought, and IUI can be a cost-effective option in selected couples.

For many patients, particularly where tubal damage, more severe male factor issues or significant age-related decline are present, IVF provides the best chance of pregnancy. IVF success rates vary with age and diagnosis, and we will discuss realistic expectations for your specific situation.

Surgical treatment may be recommended for certain uterine or pelvic conditions, for example, removing fibroids, polyps or adhesions that are thought to be affecting implantation or increasing miscarriage risk. Throughout your journey, access to counselling and emotional support is an integral part of care, recognising the unique grief that can accompany struggling to conceive after having a child.

If you are worried about secondary infertility, please arrange an initial consultation with one of our fertility experts.

My name is Dr Joe Lipton, and I am one of the team of consultant anaesthetists working here at Aria. This short blog post is designed to help you understand what to expect from your sedation when you attend the clinic for egg collection, either as part of egg freezing or IVF.

All anaesthetists at Aria are experienced consultants who also work in London teaching hospitals. Our role is to keep you safe, comfortable and well-supported throughout your procedure. When you meet your anaesthetist on the day, they will ask about your medical history, any previous experiences with sedation or general anaesthesia, and talk you through the process step by step.

Occasionally – usually for patients with particular underlying health conditions – you may need to have an anaesthetist consultation in advance to help plan your care. In rare circumstances, we may recommend sedation in a hospital setting, though this is uncommon.

Before your sedation

As part of your preparation, you will receive clear instructions on eating and drinking. It is important to follow these carefully:

  • No food or drinks containing milk for at least 6 hours before sedation
  • No drinks at all, including water, for the final 2 hours

You will still be offered a dose of paracetamol on arrival, which can safely be taken with a small sip of water. These fasting guidelines are essential for your safety, as having sedation with food or drink remaining in the stomach carries a risk of regurgitation while sedated.

During the egg retrieval procedure

In the procedure room, we will attach routine monitoring equipment and provide you with oxygen via a face mask. The anaesthetist will place a small cannula (a thin tube) into a vein in your hand or arm. Through this, we administer a strong pain-relieving medication together with a sedative. The sedative that is administered can sometimes sting, feel cold or uncomfortable for a short time as it is injected, but these sensations should pass quickly.

These medicines work quickly to produce a state of deep sedation. With deep sedation, some patients may have brief awareness or recall during the procedure; however, most patients are very relaxed, comfortable, and unaware of what is happening, and many do not remember anything from the time the medication is given until they wake up afterwards.

Your anaesthetist will remain with you throughout the procedure, carefully monitoring you and adjusting medication as needed to ensure your comfort and safety.

After your egg collection procedure

Once the egg collection is complete, we stop administering sedation, and you will wake up shortly afterwards. It is normal to feel drowsy for several minutes while the medication wears off. The nursing team will monitor you closely in recovery and ensure you are comfortable, including providing additional pain relief if needed.

Mild cramping or discomfort is common immediately after egg collection, but this usually settles quickly. Some patients feel nauseated after sedation; if you have experienced this before, please tell your anaesthetist, as we can give preventative anti-sickness medication.

The procedure itself usually takes 20–30 minutes, and you will typically spend around an hour in recovery. You can go home once you feel well, have had something to eat and drink, and have emptied your bladder. Your Anaesthetist will review you before you leave, and the nursing team will talk you through aftercare instructions. It is normal to experience some discomfort at home after your procedure, so you should stock up on simple painkillers that can be purchased over the counter.

You may continue to feel the residual effects of sedation for up to 24 hours, so you should not drive, operate machinery, or sign important documents during this time.

Further information

You may wish to watch the videos we have posted, which show the procedure room and give a clearer sense of what to expect. If you have any concerns about sedation or would like to speak with an anaesthetist in advance, the clinic can arrange this.

We wish you all the very best with your fertility journey, and we look forward to meeting you.

The holiday period is a time of indulgence, yet it can be particularly challenging for those focusing on fertility health or undergoing assisted reproductive technologies such as IVF. While festive foods often lean toward decadent treats, sugary desserts, and celebratory drinks, making mindful choices lets you enjoy seasonal fare without compromising your commitment to fertility health.

Here is our practical guide to maintaining a fertility-supportive diet over the festive period, emphasising the nutrients that promote reproductive health and strategies to stay balanced while celebrating.

Key nutrients for reproductive health

A nutrient-rich, fertility-friendly diet approach can strengthen egg and sperm health, balance hormones and reduce oxidative stress – especially valuable for anyone preparing for IVF or other fertility treatments. This can include:

Healthy fats and omega-3s

Sources: Oily fish (like salmon and sardines), chia seeds, flaxseeds and walnuts

Benefits: Omega-3 fatty acids play a vital role in hormone regulation, egg maturation, and sperm motility. Aim to limit saturated and trans fats found in heavily processed or fried holiday foods.

Antioxidant-rich foods

Sources: Berries, nuts, spinach, kale and dark chocolate

Benefits: Nutrients such as vitamins C and E, zinc, selenium, and CoQ10 help protect reproductive cells from oxidative damage. Include colourful fruit and vegetables and antioxidant-packed snacks in festive meals to support healthy gamete function.

Protein from quality sources

Sources: Fish, lean poultry, eggs, beans, lentils and tofu

Benefits: Protein supports hormonal pathways and tissue repair. Opting for lean and plant-based proteins over processed meats can enhance fertility outcomes.

Folate and B vitamins

Sources: Leafy greens, legumes and fortified grains

Benefits: Folate is crucial for DNA formation and embryo development. Regular consumption helps improve egg and sperm quality and reduces the risk of chromosomal issues.

Low glycaemic index (GI) carbohydrates

Sources: Whole grains, vegetables and pulses

Benefits: Steady blood sugar levels help maintain hormonal stability, particularly for individuals managing PCOS or insulin resistance. Choosing low-GI foods prevents energy crashes and promotes metabolic balance.

Smart strategies for balanced holiday eating

You don’t have to forgo festive enjoyment to support fertility – just plan mindfully.

  • Practice portion control: enjoy your favourite food in smaller servings to balance indulgence and nutrition.
  • Look for alcohol-free drinks: alcohol may impair egg health and sperm integrity, so celebrate with mocktails made from pomegranate or cranberry juice, sparkling water, and herbs instead.
  • Upgrade traditional recipes: instead of roasting potatoes in goose fat or lard, use healthy monounsaturated fats like olive oil or avocado oil.
  • The secret is in the timing: eating a large meal at lunchtime means we have more time to digest it and utilise the calories.
  • Walk it off: going for a good walk after lunch will improve your blood sugar levels and lift your mood.

The important thing is not to panic if you feel you’ve over-indulged over the holiday season. One or two days of enjoying festive treats won’t derail your fertility journey, so permit yourself to enjoy this Christmas and New Year without guilt.

There has been an explosion in the consumption of ultra-processed food or UPFs in recent years and it’s estimated that over 50% of the food bought in the UK now consists of UPF. Compare this with 14.2% and 13.4% for our French and Italian neighbours respectively.

In a large-scale review involving almost 10 million people around the world, UPF has been linked to 32 harmful effects to our health, including high risk of heart disease, cancer, type 2 diabetes and early mortality. While this particular review did not examine the impact of high consumption of ultra-processed foods on fertility, there is an increasing body of research into this field.

What are ultra-processed foods?

“Our consumption is so high because so much of our diet come under the banner of being a processed food in the first place,” explains dietitian Alex Ballard. “Often, we think that this just means crisps, sweets or ready meals and, while it is true that many ultra-processed foods are high in unhealthy fats, sugar, and salt, not all are ‘unhealthy’.

“So, things like fortified breakfast cereal, such as Weetabix or Shredded Wheat, wholegrain bread, low fat yogurts, hummus can be classified as processed foods yet still be part of a healthy diet.”

Indeed, there is no single, universally agreed definition for ultra-processed foods. The term itself originates from the NOVA classification system, which was created by scientists at the University of São Paulo in Brazil.

NOVA divides foods into four main categories according to how much industrial processing they undergo.

  • Unprocessed or minimally processed foods: These are natural foods like fruit, vegetables, milk, fish, pulses, eggs, nuts, and seeds that have had minimal or no alteration and no added ingredients.
  • Processed culinary ingredients: These include substances used in cooking rather than eaten alone, such as oil, sugar, and salt.
  • Processed foods: Made by blending ingredients from the first two groups, these are foods that could feasibly be prepared at home and examples include jams, pickles, canned fruits or vegetables, cheeses, and freshly baked breads.
  • Ultra-processed foods: These contain multiple industrial ingredients and additives rarely used domestically. They often feature preservatives, emulsifiers, sweeteners, and artificial colours or flavours, to give them a long shelf life.

What impact does ultra-processed food have on fertility?

Emerging evidence indicates that consuming large amounts of ultra-processed foods may adversely affect fertility in both women and men although the lack of a universal definition of what a UPF is contributes to the confusion of what we should and shouldn’t be eating.

“Although we have studies that show high consumption of these foods can produce poorer health outcomes and affect things like fertility, one research study will be testing certain foods, and another research study will test completely different foods.

“When it comes to fertility, researchers have examined the impact on both men and women, and several mechanisms are believed to play a role.”

Increased inflammation and oxidative stress

Ultra-processed foods are typically high in sugars, unhealthy fats, and artificial ingredients, all of which can trigger inflammation and oxidative damage in the body. Such effects may interfere with reproductive function by disturbing hormone regulation. In men, oxidative stress can attack sperm membranes and fragment DNA, which is linked to lower sperm motility and higher miscarriage risk.

Hormonal disturbances

Diets rich in highly processed products can disrupt hormone balance by impacting the endocrine system. For instance, spikes in insulin levels from processed sugars may impair reproductive hormones, potentially disrupting ovulation in women and reducing sperm production in men.

Depriving the body of essential nutrients

These foods often provide minimal vitamins, minerals, and antioxidants. The resulting nutrient deficiencies can affect fertility by lowering the quality of eggs and sperm.

Weight gain and metabolic problem

Frequent consumption of ultra-processed items is linked to obesity and other metabolic issues. Conditions like obesity and metabolic dysfunction are known contributors to infertility, such as polycystic ovary syndrome (PCOS) in women or diminished sperm quality in men.

In a 2025 study, healthy young men were placed on two tightly controlled diets, one high in UPFs and one composed of unprocessed foods, while ensuring that calorie intake was the same. It found that men gained fat mass on the UPF diet despite eating the same calories. As LDL cholesterol levels rose, there was a notable decrease in follicle‑stimulating hormone (FSH), a key driver of sperm production.

A fertility dietitian’s advice on UPFs

An NHS dietitian for ten years, Alex’s keen interest in female health and understanding of how diet can improve conditions such as PCOS and endometriosis led her to specialise in fertility nutrition.

“I believe we should approach UPFs in a nuanced way rather than demonising everything that falls under the banner of being processed. We should always ask ourselves, does this seem healthy? Is it nutrient dense? Does it have lots of vitamins and minerals? Is it high in fibre?

“If you’re answering yes, then then they’re going to be good things to include. Even the foods that do not have a lot of nutritional value can still have a place. Typicallly, they taste good and absolutely we can have food just for enjoyment’s sake. However, if we are having them in large quantities on a regular basis over a long period of time, then they are likely to have a detrimental impact on our health.

“I think it’s also important to highlight that sometimes we hear the word additives, and we think that’s a negative, whereas it can mean nutrient fortification, including added calcium vitamin D, or iodine, and that’s a positive. Or it could be quite a natural ingredient that is making the food safer to consume, increasing the shelf life, or making it more affordable so it’s accessible for more people.”

Alex’s tips on navigating UPFs:

  • Try to be organised with food planning and prep so you don’t reach for convenience foods which are likely to be ultra processed.
  • Take a packed lunch into work or take snacks out with you when you’re on the go.
  • Try to cook meals from scratch if you can as you’re likely to use ingredients in their naturally occurring form.
  • You don’t have to abstain completely but look at your consumption and try to reduce it down and switch over to natural foods as much as possible.
  • Look at the ingredients list on foods you’re considering consuming. As a very general rule, if there is only a small handful of ingredients, most of which you recognise or have a place in the domestic kitchen, then the food is likely to have gone through a minimal amount of processing. Whereas a long list of ingredients that you don’t recognise is a red flag.

For more advice on fertility nutrition, please visit our support hub or arrange a consultation with Alex Ballard.

Egg freezing has exploded in popularity, as more and more women want to improve their chances of starting a family at the time that’s right for them, without feeling tied down by the biological clock.

In fact, according to statistics from the Human Fertilisation and Embryology Authority, the number of women choosing to freeze their eggs has risen by 460% in the past 25 years.

What is egg freezing?

If you haven’t joined the ranks of women freezing their eggs yet, you may be wondering what the process involves. Essentially, egg freezing is a procedure to harvest mature eggs and then freeze them so they can be fertilised in future.

Usually, we only produce one mature egg a month, so to make the process quicker, hormones are injected to stimulate the ovaries to produce more eggs. This egg production usually takes between 10 and 14 days, and then the eggs are harvested in a short procedure, and then frozen and stored until you are ready to use them.

The harvesting procedure itself is carried out under light sedation and most women report it to be quick and painless.

Is there an optimal age for egg freezing?

Theoretically, eggs can be harvested and frozen at any time before menopause, but is there an optimal time to do it?

The answer depends on several factors and will be different for everyone. Generally speaking, the factors to be considered are:

  • Egg quality – as a rule, the younger you are, the better the quality of your eggs. So ideally, if this was the only consideration, the younger the better. By the age of 35, the quality of your eggs begins to decline quite rapidly
  • Finances – egg freezing is not a cheap option, costing something in the region of £7,000. If you are in your early 20s, you may not be as financially stable as someone in their 30s, so cost may be a consideration
  • Usefulness – how likely is it that you will need to use these eggs? At 21, you have a high chance of natural conception, and your frozen eggs may never be used.

Are there any other considerations?

There are lots of things to think about when it comes to freezing your eggs. Whatever your age, the financial aspect is worth considering. However, many women feel that the reassurance of having their eggs safely stored away for future use gives them peace of mind, as it allows them to focus on their career without worrying about settling down before it’s too late.

There is also an emotional angle to consider – hormone injections notwithstanding, egg freezing can be a daunting process. You might feel a mixture of relief and empowerment at taking control of your own fertility, with anxiety about the procedures or even guilt at putting your career before your unborn child.

Here at Aria, we are experienced in helping women consider all these aspects and we pride ourselves on talking you through the process totally impartially, so you don’t feel any pressure to make a decision that may not be right for you.

If this is something you would like to discuss, please contact us to make an appointment today.

This month, we’re speaking to fertility dietitian Alex Ballard (@alextalksdiet), who specialises in preconception nutrition and offers support to Aria Fertility patients.

What are your qualifications and experience as a dietitian?

I qualified as a dietitian in 2015 following a four-year degree involving various clinical placements. These included specialties such as paediatrics, intensive care, oncology and surgery.

Since then, I have worked in the NHS for ten years, seeing patients from all walks of life needing nutritional support. A lot of my current NHS work focuses on diabetes, cardiovascular disease, menopause and elderly care within GP surgeries.

Five years ago, I started my private practice as a specialist fertility dietitian following extensive research and additional training. I have advised hundreds of clients on diet and fertility, fertility treatment and foetal development.

I am a member of the British Dietetic Association and am HCPC registered.

What is the most rewarding part of your role as a fertility dietitian?

That is easy!

Firstly, clients’ feedback that they felt listened to, not judged, and were motivated to make changes following our session.

Secondly, getting updates from past clients to say they are pregnant. I love hearing back from clients to know how their journey is going.

What do you consider to be a healthy diet?

The reason it is so valuable to see a dietitian is that a ‘healthy diet’ can look incredibly different from person to person.

It is fantastic that diet is such a powerful tool for helping with fertility and managing health conditions (such as PCOS, diabetes, coeliac disease and endometriosis), but it’s essential that advice is personalised to an individual.

In general, balance is key! All foods can be part of a healthy, balanced diet. However, focusing on adding a variety of different colours and maximising naturally occurring foods is a helpful foundation for most people.

What inspired you to get into fertility nutrition?

I have always had a keen interest in female health and understanding how diet can improve symptoms for conditions such as PCOS, hypothalamic amenorrhea and endometriosis. This likely started following some of my own hormonal issues.

I started reading the research available on how diet can impact fertility and was astonished that nutrition wasn’t being talked about more in this space. I really wanted to use my knowledge to help individuals on their fertility journey and give them back some control.

What can clients expect when they work with you?

A friendly face and a non-judgemental conversation. My private consultations are relaxed and involve working together to formulate realistic nutritional goals.

My consultations are online, and an initial appointment ranges from 60 to 75 minutes. I can see individuals or couples.

We will start by getting to know each other and you explaining your goals. Then we will gather information about your current dietary intake and lifestyle. Following this, we will discuss relevant information about how nutrition can help you and together agree on what you want to work on first.

Review appointments are also available so that we can chat about how things have gone, discuss any challenges and add in some more changes when the time is right.

What are the most common challenges that your fertility clients face?

Often, my fertility clients may have multiple nutritional needs alongside trying to conceive and, for example, have a health condition that is impacted by diet (such as PCOS, high blood pressure, IBS), an allergy or intolerance to particular foods or food preferences (such as following a vegan diet).

Typically, in these cases, there can be so much information – often conflicting – that they are left confused and unsure of what to do.

A dietitian can help unpick this and make sure the agreed goals are appropriate for all of your needs.

Do you have one piece of advice for couples or individuals trying to conceive?

There can be too much of a good thing. Always have a sensible hat on when you hear advice about food.

It is fantastic that particular nutrients can be so helpful for fertility. However, it is always good to have a wide variety of ingredients instead of overloading on the same specific foods.

Yes, red/pink fruits and vegetables are helpful for lycopene. No, you do not have to drink glasses of beetroot juice each day.

Yes, a preconception supplement can be helpful for some people. No, you do not need to take three different ones or spend a fortune.

Yes, eating more nuts and seeds can be fantastic for fertility. No, restricting yourself to just seed cycling is not necessary.

Contact fertility dietitian Alex Ballard for more advice. We work closely with a wide range of practitioners to provide support throughout your fertility journey – click here to visit our Support Hub.

A new study has been published in the Journal of Clinical Medicine, exploring the benefits of genetic testing for IVF-created embryos in women over 35.

Conducted by a research team from King’s College London, King’s College Hospital and King’s Fertility, this was the first study of its kind to look specifically at women aged 35 plus, and found that genetic screening of embryos could help women aged 35-42 successfully conceive in a shorter timeframe.

Although the sample size was too small to be considered statistically significant, the positive difference in cumulative live birth rate in those women who underwent genetic screening was large enough (72% compared to 52% in the control group) that the researchers believe the study merits a larger, multi-centre trial.

This could be exciting news for the IVF community, but genetic screening is not suitable for everyone, so here at Aria we’ve put together a list of FAQs to help you decide if it’s right for you.

What is genetic screening?

Genetic screening is a process that allows embryologists to check embryos that have been created through IVF for genetic and/or chromosomal abnormalities.

There are three different types of embryo screening:

PGT-A (aneuploidy testing)

This is the most common form of embryo screening and is looking for a genetic disorder called Aneuploidy. This is a condition that results in cells with either too many or too few chromosomes, potentially leading to life-limiting conditions such as Edward Syndrome or Patau Syndrome, and increasing the risk of miscarriage. During PGT-A screening, any embryos with more or less than the standard 46 chromosomes are not considered for transfer to the uterus.

PGT-M (monogenic testing)

Monogenic means single gene, so this test is looking for disorders associated with a single gene. PGT-M looks for specific genes carried by one or both parents, that might indicate genetic disorders like sickle cell anaemia or cystic fibrosis. Only embryos that are free of this specific gene would be transferred.

PGT-SR (structural rearrangements)

PGT-SR is looking for structural issues in the chromosomes, like segments that have been inverted, duplicated or are missing. Ensuring only embryos without these structural issues are implanted in the womb reduces the risk of failed implantation, miscarriage, birth defects or developmental issues.

How is genetic screening carried out?

The process is similar for all types of embryo screening:

  1. First, the embryos are created through IVF
  2. When the embryos reach five to six days old, a few cells are taken from the outer layer of each embryo
  3. The embryo is then frozen for the four to six weeks it takes for genetic testing to take place
  4. The cells that have been removed from the embryos are taken for genetic analysis
  5. Embryos that have been identified as healthy, without any genetic abnormalities, are then transferred to the uterus
  6. The usual IVF process continues

Who is suitable for genetic screening in IVF?

This process is not suitable for everyone. If you are younger than 35 and have no known risk factors, this could be an unnecessary additional step in the process. However, genetic screening can potentially help you achieve a viable pregnancy faster if:

  • You are over 35 – the older you are, the higher the risk of chromosomal abnormalities
  • You have a history of repeated miscarriage – some genetic disorders can increase the risk of miscarriage
  • You or your partner has a family history of genetic disorders
  • You are experiencing unexplained infertility or have undergone several failed IVF cycles

If you would like to know more about genetic screening in IVF and find out whether it might be helpful for you, one of our team will be happy to talk you through the process. Please contact us to make an appointment.

GET IN TOUCH.

This contact form is deactivated because you refused to accept Google reCaptcha service which is necessary to validate any messages sent by the form.

OPENING HOURS.

Mon – Fri: 9am – 5pm

CLINIC LOCATION.

8 Welbeck Way  London  W1G 9YL

CONTACT US.

+44 (0) 203 263 6025

admin@ariafertility.co.uk

Fertility Clinic London Location

Authorised by the Human Fertilisation Embryology Authority

LEGAL ARIA PATIENT PORTAL