The HBA test is designed to provide a qualitative assessment of sperm quality, maturity, and fertilising potential to diagnose suspected male infertility. It allows our Embryologists to distinguish between mature sperm that express hyaluronan receptors (key for egg-sperm recognition) and those that do not.
The results help us to advise you about whether treatment with conventional IVF or ICSI is more likely to be successful. Approximately 48% of infertile patients have abnormal results (low binding) despite having normal DNA fragmentation.
If the proportion of bound sperm is low, then it is possible to pre-select mature sperm in the lab during your fertility treatment. At Aria we offer an insemination technique (PIMSI) that unites the two more specialised forms of sperm selection: physiological ICSI (PICSI) and Intracytoplasmic Morphologically Selected Sperm Injection (IMSI).
PIMSI has been reported to increase pregnancy rates when compared with IMSI alone, though it has not been tested in larger trials and requires further investigation. The clinic will only offer it when your consultant deems it appropriate for your treatment.